- Ron's Finders Keepers Shop
- Rosalie's
- Rosenbaum's Nursery
- Rosenberry's Abattoir Inc
- Rosenberry's Electrical Svc
- Rotunda Group
- Rotz & Stonesifer Accountants
- Rotz Brick & Block Inc
- Rotz Golf Club Repair Svc
- Rotz Oil
- Rotz's Hauling & Dumpster Svc
- Round House Kitchen
- Roundhouse Relics
- Route 11 Glass
- Route 5
- Route 5 Gifts
- Roxbury Treatment Ctr
- Roy A Himelfarb Inc
- RPM Motors
- Russ Naugle Auto Sales & Rpr
- Russell R Berry Towing
- Rwr Construction Inc
- Ryan & Assoc
- Ryan's Grill Buffet & Bakery
- Ryder Supply Co
- Ryder Truck Rental One Way Inc
- Ryder's Backhoe Inc
- S & A Custom Built Homes Inc
- S & S Advertising Products
- S & S Electric Motors Inc
- S & S Silk Screening
- S & S Wildlife Control Svc Inc
- S & T Clock Shop
- S D Designs LTD
- Safelite Auto Glass
- Saidis Shuff Flower & Lindsay
- Salem United Brethren Church
- Sally Beauty Supply
- Salvation Army
- Salvation Army Thrift Store
- Salzmann & Hughes
- Sam Fisher
- Sanctuary House-Chambersburg
- Sanders Brothers Tree Svc
- Sandy's Beauty Salon
- Sandy's Bridals
- Sandy's Warm Spring Svc
- Sarlin Rentals
- Satyajit Mukherjee MD
- Sboca Wireless Network
- Schier's Furniture
- Schlichter Financial Svc
- Schoenberger's Restaurant
- Schoeneman Beauty Supply
- Schultheiss & Assoc
- Science Applications Intl Corp
- Scotland Orchard
- Scotland Podiatric PC
- Scottee Coin Wash
